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Sarcopenia and fall-related injury among older adults in five low- and middle-income countries

journal contribution
posted on 2023-08-30, 18:07 authored by Nicola Veronese, Lee Smith, Mario Barbagallo, Lin Yang, Liye Zou, Josep Haro, Ai Koyanagi
Sarcopenia is a common condition in older people and increasing evidence suggests that it can be considered as a potential risk factor for falls and fractures. However, no studies on this topic from low- and middle-income countries (LMICs) are available. Thus, we assessed this association among older adults from five LMICs (China, India, Ghana, Mexico, and Russia). Community-based, nationally representative, cross-sectional data of the Study on Global Aging and Adult Health were analyzed. Sarcopenia was defined as the presence of low skeletal muscle mass based on indirect population formula, and either slow gait or low handgrip strength. The presence of fall-related injury was ascertained through self-reported information. Multivariable logistic regression analysis and meta-analysis were conducted. The sample consisted of 13,101 individuals aged ≥65 years (mean (SD) age 72.6 (11.3) years; 45% males). The prevalence of fall-related injury was higher among those with sarcopenia than in those without this condition (e.g., Mexico 9.8% vs. 2.7%). Adjusted analyses showed that sarcopenia was associated with a 1.85 (95%CI = 1.24–2.77) times higher odds for fall-related injury, with a low level of between-country heterogeneity. Future studies of longitudinal design may shed light on whether sarcopenia in LMICs may be considered as a risk factor for falls.

History

Refereed

  • Yes

Volume

147

Page range

111262

Publication title

Experimental Gerontology

ISSN

1873-6815

Publisher

Elsevier

File version

  • Accepted version

Language

  • eng

Legacy posted date

2021-01-27

Legacy creation date

2021-01-27

Legacy Faculty/School/Department

Faculty of Science & Engineering

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