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The separate and joint effects of recent interpersonal abuse and cannabis use on psychotic experiences: Findings from students in higher education in the United States

journal contribution
posted on 2023-08-30, 20:32 authored by Hans Oh, Jinyu Du, Nicole Karcher, Els Van der Ven, Jordan DeVylder, Lee Smith, Ai Koyanagi
Background Various forms of interpersonal abuse (e.g., physical, emotional, sexual) and cannabis use across the lifespan have both been known to increase odds of psychotic experiences; however, there have been few studies examining their separate and joint efects in the United States. Methods We analyzed data from the Healthy Minds Study (2020–2021) and used multivariable logistic regression and interaction contrast ratios to assess separate and joint efects of interpersonal abuse (past 12 months) and cannabis use (past 30 days) on psychotic experiences (past 12 months). Results Students who only used cannabis had signifcantly greater odds of psychotic experiences (aOR: 1.70; 95% CI 1.58–1.82), as well as those who only experienced interpersonal abuse (aOR: 2.40; 95% CI 2.25–2.56). However, those who reported both cannabis use and interpersonal abuse had the greatest odds, exceeding the sum of these individual efects (the combined efect aOR: 3.46; 95% CI 3.19–3.76). Conclusions Recent interpersonal abuse and recent cannabis use both separately and jointly increase odds of having recent psychotic experiences. Future research should continue to examine the potential interactive and additive impact of multiple known exposures to better inform primary and secondary prevention eforts.

History

Refereed

  • Yes

Publication title

Social Psychiatry and Psychiatric Epidemiology: the international journal for research in social and genetic epidemiology and mental health services

ISSN

1433-9285

Publisher

Springer

File version

  • Accepted version

Language

  • eng

Legacy posted date

2023-05-10

Legacy creation date

2023-05-10

Legacy Faculty/School/Department

Faculty of Science & Engineering

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