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The association of physical multimorbidity with suicidal ideation and suicide attempts in England: A mediation analysis of influential factors

journal contribution
posted on 2023-09-01, 15:04 authored by Lee Smith, Jae Il Shin, San Lee, Jae Won Oh, Guillermo Lopez-Sanchez, Karel Kostev, Louis Jacob, Mark Tully, Felipe Schuch, Daragh McDermott, Damiano Pizzol, Nicola Veronese, Junmin Song, Pinar Soysal, Ai Koyanagi

Background:

Suicide is one of the most important causes of deaths in the United Kingdom, and the numbers are currently increasing.

Aim:

There are numerous identified determinants of suicidality, and physical multimorbidity is potentially important but is currently understudied. Thus, this study aims to investigate the association of physical multimorbidity with suicidality.

Methods:

Cross-sectional data from the Adult Psychiatric Morbidity Survey 2007, which was conducted in England between October 2006 and December 2007 by the National Center for Social Research and Leicester University were analyzed. Respondents were asked about 20 physical health conditions, and suicidal ideation and suicide attempts were assessed.

Results:

Out of 7,403 individuals aged 16 years or over, the prevalence of physical multimorbidity, suicidal ideation, and suicide attempts were 35.1%, 4.3%, and 0.7%, respectively. After adjustment for potential confounders, compared to no physical conditions, 1, 2, 3, and ⩾4 conditions were associated with significant 1.79 (95% CI [1.25, 2.57]), 2.39 (95% CI [1.63, 3.51]), 2.88 (95% CI [1.83, 4.55]), and 6.29 (95% CI [4.12, 9.61]) times higher odds for suicidal ideation. Mediation analysis showed that cognitive problems (mediated percentage 39.2%) and disability (37.5%) explained the largest proportion between multimorbidity and suicidal ideation. Pain (38.0%) and cognitive problems (30.7%) explained the largest proportion between multimorbidity and suicide attempts.

Conclusion:

In this large sample of UK adults, physical multimorbidity was associated with significantly higher odds for suicidal ideation and suicide attempts. Moreover, several potential mediators were identified, and these may serve as future targets for interventions that aim to prevent suicidality among people with physical multimorbidity.

History

Refereed

  • Yes

Volume

69

Issue number

3

Publication title

International Journal of Social Psychiatry

ISSN

1741-2854

Publisher

SAGE Publications

File version

  • Accepted version

Language

  • eng

Legacy posted date

2022-11-21

Legacy creation date

2022-11-21

Legacy Faculty/School/Department

Faculty of Science & Engineering

Affiliated with

  • School of Psychology and Sport Science Outputs

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