Asaad_et_al_2021.pdf (2.28 MB)
The Rare Diagnosis of Synchronous Breast and Colonic Cancers: A Case Report and Review of Literature
journal contribution
posted on 2023-07-26, 15:19 authored by Amira Asaad, Marina Barron, Noreen Rasheed, Philip Idaewor, Abdalla Saad Abdalla Al-ZawiAny two or more primary malignant tumors, in which each tumor is not an extension, recurrence, or metastasis of the other lesion, are defined or described as multiple primary malignant neoplasms (MPMN). These tumors are increasingly diagnosed despite their rare occurrence rate. The term synchronous tumors is applied if two different tumors originating in the same patient are detected at the same time or within six months; if the second tumor is detected beyond six months, it is called metachronous. Aetiological factors that may predispose patients to MPMNs have been grouped into three broad categories: familial cancer syndromes and other genetic susceptibility factors, common exposures (e.g. tobacco), and carcinogenic effects of cancer treatment. The likelihood of missing asymptomatic synchronous tumors at the time of diagnosis is due to a lack of definitively set guidelines for synchronous tumors. Studying every individual case may aid us in understanding disease biology, developing diagnostic guidelines, and establishing patient-specific management strategies. We present a case report of synchronous breast and colonic cancer in a female patient.
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13Issue number
2Page range
e13314Publication title
Cureus Journal of Medical ScienceISSN
2168-8184External DOI
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Cureus, IncFile version
- Published version
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- eng
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2021-03-29Legacy creation date
2021-03-29Legacy Faculty/School/Department
Faculty of Health, Education, Medicine & Social CareUsage metrics
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