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Neutralisation of SARS‐CoV‐2 by anatomical embalming solutions

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posted on 2023-07-26, 15:34 authored by Fabio Quondamatteo, Dora E. Corzo‐Leon, Cecilia Brassett, Ian Colquhoun, David C. Davies, Peter Dockery, Sue Grenham, Simon Guild, Amanda Hunter, James Jones, Thomas C. Lee, Chris Tracey, Tracey Wilkinson, Carol A. Munro, Thomas H. Gillingwater, Simon H. Parson
Teaching and learning anatomy by using human cadaveric specimens has been a foundation of medical and biomedical teaching for hundreds of years. Therefore, the majority of institutions that teach topographical anatomy rely on body donation programmes to provide specimens for both undergraduate and postgraduate teaching of gross anatomy. The COVID-19 pandemic has posed an unprecedented challenge to anatomy teaching because of the suspension of donor acceptance at most institutions. This was largely due to concerns about the potential transmissibility of the SARS-CoV-2 virus and the absence of data about the ability of embalming solutions to neutralise the virus. Twenty embalming solutions commonly used in institutions in the United Kingdom and Ireland were tested for their ability to neutralise SARS-CoV-2, using an established cytotoxicity assay. All embalming solutions tested neutralised SARS-CoV-2, with the majority of solutions being effective at high-working dilutions. These results suggest that successful embalming with the tested solutions can neutralise the SARS-CoV-2 virus, thereby facilitating the safe resumption of body donation programmes and cadaveric anatomy teaching.

History

Refereed

  • Yes

Volume

239

Issue number

5

Page range

1221-1225

Publication title

Journal of Anatomy

ISSN

1469-7580

Publisher

Wiley

File version

  • Published version

Language

  • eng

Legacy posted date

2021-10-28

Legacy creation date

2021-10-28

Legacy Faculty/School/Department

COVID-19 Research Collection

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