Anglia Ruskin Research Online (ARRO)
Browse

Early Endothelialization of Ab Interno Stromal Tectonic Patch in the Management of Corneal Perforation Secondary to Bacterial Keratitis

journal contribution
posted on 2023-07-26, 15:53 authored by Harry W. Roberts, Max Davidson, Caroline Thaung, James Myerscough
Purpose: The purpose of this study was to describe a novel surgical technique using an ab interno stromal patch to treat corneal perforation and to present the histological findings of the patch after its removal during definitive mushroom keratoplasty. Methods: The endothelium had already been removed with the submerged cornea using backgrounds away (SCUBA) technique. Results: The patient was managed successfully with a sutureless ab interno stromal tectonic patch. Two months later, definitive mushroom keratoplasty was performed and the patch was sent for histological examination. Immunohistochemistry revealed a reactive endothelium covering the posterior surface of the graft. Nine months later, her best-corrected visual acuity was 6/9. Conclusions: This is the first case to our knowledge demonstrating that stromal tectonic grafts without the endothelium can successfully attach to the host tissue and seal a perforation. The stroma may undergo reendothelialization and begin to restore vision, even before penetrating keratoplasty.

History

Refereed

  • Yes

Volume

41

Issue number

6

Page range

802-805

Publication title

Cornea

ISSN

1536-4798

Publisher

Lippincott, Williams & Wilkins

Language

  • other

Legacy posted date

2022-06-06

Legacy Faculty/School/Department

Faculty of Health, Education, Medicine & Social Care

Usage metrics

    ARU Outputs

    Categories

    No categories selected

    Keywords

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC