posted on 2024-04-10, 08:46authored byPeter Richardson, Ivan Griffin, Catherine Tucker, Dan Smith, Olly Oechsle, Anne Phelan, Michael Rawling, Edward Savory, Justin Stebbing
Given the scale and rapid spread of the 2019 novel coronavirus (2019-nCoV) acute respiratory disease, there is an immediate need for medicines that can help before a vaccine can be produced. Results of rapid sequencing of 2019-nCoV, coupled with molecular modelling based on the genomes of related virus proteins,1 have suggested a few compounds that are likely to be effective, including the anti-HIV lopinavir plus ritonavir combination...